منابع مشابه
Twenty Years of AIRE
About two decades ago, cloning of the autoimmune regulator (AIRE) gene materialized one of the most important actors on the scene of self-tolerance. Thymic transcription of genes encoding tissue-specific antigens (ts-ags) is activated by AIRE protein and embodies the essence of thymic self-representation. Pathogenic AIRE variants cause the autoimmune polyglandular syndrome type 1, which is a ra...
متن کاملTwenty years of technology.
In looking back at previous issues of RNA and my own eight RNA papers, what strikes me, in addition to all the great science that’s been published in our society journal over the past 20 years, is the evolution (or more properly, revolution!) in the methods and technologies we use. Equally striking has been the exponential increase in the amount of data in each published paper. In two decades, ...
متن کاملTwenty years of marriages.
In 1994, a total of 159,959 marriages were performed in Canada, up only slightly from 159,316 the year before. This small increase had no effect on the crude marriage rate, which remained at 5.5 marriages per 1,000 population. Aside from a brief uptum in the late 1980s, Canada's marriage rate has fallen quite steadily since the early 1970s. The overall decline is also evident when rates are dis...
متن کاملTwenty Years of Reflections
As I was reflecting deeply in front of the statue of Bodhisattva of Gr~ and Wisdom in the University Muset~n, I was startled to see Jane. Having heard from Don that he had asked the old cats to reflect on the 20 years of ACL, Jane had decided that she should drop in on some of them to seek their advice concerning the future of ACL. I wish to thank Alice, the Cheshire Puss, and Lewis Carroll for...
متن کاملTwenty Years of KSHV
Twenty years ago, Kaposi's sarcoma (KS) was the oncologic counterpart to Winston Churchill's Russia: a riddle, wrapped in a mystery, inside an enigma. First described by Moritz Kaposi in 1872, who reported it to be an aggressive skin tumor, KS became known over the next century as a slow-growing tumor of elderly men-in fact, most KS patients were expected to die with the tumor rather than from ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2018
ISSN: 1664-3224
DOI: 10.3389/fimmu.2018.00098